Protein Info for AO353_06345 in Pseudomonas fluorescens FW300-N2E3

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 795 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 182 to 204 (23 residues), see Phobius details amino acids 211 to 234 (24 residues), see Phobius details amino acids 244 to 267 (24 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 334 to 356 (23 residues), see Phobius details amino acids 363 to 383 (21 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 31 to 170 (140 residues), 140.1 bits, see alignment E=1.1e-44 PF07695: 7TMR-DISM_7TM" amino acids 183 to 385 (203 residues), 196 bits, see alignment E=1.8e-61 PF00512: HisKA" amino acids 418 to 482 (65 residues), 56.6 bits, see alignment E=5.5e-19 PF02518: HATPase_c" amino acids 529 to 642 (114 residues), 69.6 bits, see alignment E=7.5e-23 PF00072: Response_reg" amino acids 673 to 780 (108 residues), 57.3 bits, see alignment E=4.1e-19

Best Hits

KEGG orthology group: None (inferred from 80% identity to pfo:Pfl01_4944)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WER8 at UniProt or InterPro

Protein Sequence (795 amino acids)

>AO353_06345 histidine kinase (Pseudomonas fluorescens FW300-N2E3)
MRYLLMLLLSLPMLAAAADFDELTQSLPLGRVMQVYEDVAGTASIADVRAQAAAGNFKTH
DKDTLNAGYSHSAFWLKVDLHYRPKDPDAQRRWLLELAYPPMDHIDLYVPDSTGEYRLVS
RTGDTLPFASRQVRQNNYLFKLDFVPDQRETLYLRLQSEGSIQAPLTLWSSTAYLEDQPL
RLYVLGLIYGVLLGMLVYNLFIYLSVRDTSYLYYIFYIGSFGLYQLSVNGAAVEYFWPNN
PWWANASTPFFIGSAALFGSQFARSFLQTASCSRWLDRLLLVLIACSAVVVGLSLMTSYA
LALRLATALALIFTVVIFFAGIFAWWRGLRVARYFIIAWSAFLLGGVVNTLMVLGYLPNM
FLTMYASQIGSAIEVALLSLALADRINAMREQQAQTLFDAGQKLEVLNQQLARSNQLKDE
FLATLTHELRTPMNGVIGSLELMQTVDLDPELEQYQQTAAGSARDMMRMVNGILTLTELQ
AGRLKVYPEAFSLRAMVETLQQQFAANAASKALDFKVDLTPGLPDRLHGDSAKLAQSLEC
LLDNAIKFTRVGGLALRVSGKFAEEGRLALSFAVIDTGIGFTDLGEATLYQRFFQLDGSM
TREYGGLGVGLAICRQLVELLGGRLTHRSEPGRGSRFQLDVEFDVVNVVQPVVAQSRQVH
GSVRLRAPQDCAVLLVDDNSINQLVVRGMLLKLGYRVRSADSGEAALEFLRRESFDAVLI
DCPLPLLDGLSIDSRIRALPGYAELPVLAAVVSAQGLDLEQGLTDYLGKPVKFEELQATL
YRRVLCPKQGESADI