Protein Info for AO353_05960 in Pseudomonas fluorescens FW300-N2E3
Annotation: anthranilate dioxygenase reductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 62% identical to ANTDC_ACIAD: Anthranilate 1,2-dioxygenase electron transfer component (antC) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
KEGG orthology group: K11311, anthranilate dioxygenase reductase (inferred from 78% identity to pfl:PFL_0757)MetaCyc: 62% identical to anthranilate dioxygenase reductase component (Acinetobacter baylyi ADP1)
Anthranilate 1,2-dioxygenase (deaminating, decarboxylating). [EC: 1.14.12.1]
Predicted SEED Role
"benzoate dioxygenase, ferredoxin reductase component; Anthranilate dioxygenase reductase"
MetaCyc Pathways
- anthranilate degradation I (aerobic) (1/1 steps found)
- 2-nitrobenzoate degradation II (1/3 steps found)
- superpathway of aromatic compound degradation via 3-oxoadipate (18/35 steps found)
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate (11/42 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.14.12.1
Use Curated BLAST to search for 1.14.12.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0N9VQY9 at UniProt or InterPro
Protein Sequence (340 amino acids)
>AO353_05960 anthranilate dioxygenase reductase (Pseudomonas fluorescens FW300-N2E3) MNHKVAFSFADGKTLFFPVQANEILLDAALRNGINIPLDCREGVCGTCQGRCESGDYSQD YVDEEALSSLDLQQRKMLTCQTRVKSDAAFYFDFASSLCNAAGPEQLSGTVTHVRQVSTS TAILHLDLGAATQPLDFLPGQYARLLIPGTMSKRSYSFANRPSSSNQLQFLIRLLPDGVM SNYIRERCQVGDEIALEAPLGAFYLRHIARPLILVAGGTGLSALLGMLDEIVARGCEQPV HLYYGVRDAADLCEGERFSAYAHRIPGFRYTPVVSDPSPGWEGKRGYIAEHFDACELRDA AVDMYVCGPPPMVESIKRWLQDQTLENVQLYYEKFTDSNV