Protein Info for AO353_04140 in Pseudomonas fluorescens FW300-N2E3

Annotation: glutaredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 113 TIGR00365: monothiol glutaredoxin, Grx4 family" amino acids 4 to 100 (97 residues), 145 bits, see alignment E=3.2e-47 PF00462: Glutaredoxin" amino acids 16 to 80 (65 residues), 66.1 bits, see alignment E=1.3e-22

Best Hits

Swiss-Prot: 69% identical to GLRX4_SHIFL: Glutaredoxin 4 (grxD) from Shigella flexneri

KEGG orthology group: K07390, monothiol glutaredoxin (inferred from 91% identity to ppw:PputW619_1110)

Predicted SEED Role

"Glutaredoxin-related protein" in subsystem Glutaredoxins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N7GZG5 at UniProt or InterPro

Protein Sequence (113 amino acids)

>AO353_04140 glutaredoxin (Pseudomonas fluorescens FW300-N2E3)
MDIIETIKEQIANNTILLYMKGSPNAPQCGFSAKAAQAVMGCGEKFAYVDILQNPEIRAN
LPKYANWPTFPQLWVAGELVGGSDIMTEMAADGSLQALIKDAAAKAAAGKTEA