Protein Info for AO353_03900 in Pseudomonas fluorescens FW300-N2E3

Annotation: disulfide bond formation protein DsbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details amino acids 51 to 70 (20 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 107 to 129 (23 residues), see Phobius details amino acids 141 to 162 (22 residues), see Phobius details amino acids 168 to 189 (22 residues), see Phobius details amino acids 202 to 223 (22 residues), see Phobius details amino acids 234 to 251 (18 residues), see Phobius details amino acids 272 to 294 (23 residues), see Phobius details amino acids 307 to 326 (20 residues), see Phobius details amino acids 338 to 355 (18 residues), see Phobius details amino acids 361 to 384 (24 residues), see Phobius details amino acids 404 to 425 (22 residues), see Phobius details amino acids 471 to 492 (22 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 17 to 422 (406 residues), 252.6 bits, see alignment E=3.8e-79 PF07690: MFS_1" amino acids 21 to 413 (393 residues), 187.5 bits, see alignment E=5.1e-59 PF00083: Sugar_tr" amino acids 50 to 179 (130 residues), 47.6 bits, see alignment E=1.8e-16 PF06609: TRI12" amino acids 60 to 420 (361 residues), 45.1 bits, see alignment E=8.3e-16

Best Hits

KEGG orthology group: None (inferred from 89% identity to pfo:Pfl01_4479)

Predicted SEED Role

"drug resistance transporter, EmrB/QacA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VQ22 at UniProt or InterPro

Protein Sequence (505 amino acids)

>AO353_03900 disulfide bond formation protein DsbA (Pseudomonas fluorescens FW300-N2E3)
VTNLNQPDSTKPAIRSVLVSLMLAIFLGALDQTIVAVSMPAISAQFKDFSLLAWVIAGYM
VAMTVAVPIYGKLGDLYGRRRLMLFGMGLFTLASVFCGMAQSMEQLVLARIFQGIGAGGM
ISVSQAIIGDIVPPRERGRYQGYFSSMYAVASVAGPVLGGYMTEYLSWRWVFLINLPLGL
GAWLVANRTLVGLPVPQRKPVIDYLGTLLMIIGLTALLLGITQVGQGHSWRSSEVLGLLA
CAVLTLTLFVWHERRAREPLLPMHLFANRNALLCWCTIFFTSFQAISLIVLMPLRFQSVT
GAGADSAALHLLPLAMGLPMGAYFAGRRTSVTGRYKPMILTGALLTPIAILGMAFSPPQA
MLISSAFMLLSGIATGMQFPTSLVGTQNSVEQRDIGVATSTTNLFRSLGGAVGVALMSAL
LLALLQDSSFAHLTGSSLIAEGSSGNVLLDGLNAAPGETQNALRAELLLTFQHLLMVSAA
VSLLGLAAAIAMPNKVLRGREDKVR