Protein Info for AO353_03650 in Pseudomonas fluorescens FW300-N2E3

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 transmembrane" amino acids 16 to 42 (27 residues), see Phobius details amino acids 155 to 179 (25 residues), see Phobius details PF00672: HAMP" amino acids 185 to 234 (50 residues), 34.6 bits, see alignment 4.8e-12 TIGR00229: PAS domain S-box protein" amino acids 288 to 403 (116 residues), 28 bits, see alignment E=1e-10 PF00989: PAS" amino acids 289 to 394 (106 residues), 43.7 bits, see alignment E=6.6e-15 PF08448: PAS_4" amino acids 294 to 397 (104 residues), 33.9 bits, see alignment E=8.3e-12 PF02518: HATPase_c" amino acids 552 to 664 (113 residues), 81.2 bits, see alignment E=2e-26

Best Hits

KEGG orthology group: None (inferred from 92% identity to pfl:PFL_4777)

Predicted SEED Role

"Sensory box histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9W1E4 at UniProt or InterPro

Protein Sequence (679 amino acids)

>AO353_03650 histidine kinase (Pseudomonas fluorescens FW300-N2E3)
MPLRQRLENLPVGQKLLAALLVLLTTVLLVANLTFISAAYWISQESMAPQALQTIGRLVA
NPSIADQALNSPEEAQRLLNELNSYSPLRAAALYDGKGLRLAQVQHGDKLKLPEHYRNIE
AWQASEFRSNQLITLLRPGEAPGHLLLVASSELPMAFYTGTLTASLGILIFSVLLWLVIA
RQIKRLITRPIHELEELSRQVTREENYALRASRGNHDEIGSLAEAFNTMLSRIEAREQQL
KRARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAL
IALDEQLYVTQWNQEASALSGTRLDEALNQPIFLAFEPLKPFLPQLRETVEQHSVVKIER
VTWVKDDEPKHYALTFYPLMGGAGRGVVIRIDDITQRLSLEEMMVQSEKMLSVGGLAAGM
AHEINNPLGAILHNVQNIRRRLSADLPKNIETAEQIGIELDSVNRYLQNREVPQLLDGIQ
QAGARAAKIVTHMLSFSRRSNRQMAPCDLPALIDQAVEIASNDFDLAIGFDFKGQAIIRQ
FDPQLGPVPGTANELEQVLLNLLKNAAQAIHQRENATEPGRIILRTRLNPPWAEIQVEDN
GVGMSENVRKRTFEPFFTTKEIGQGTGLGLSVSYFIITNNHKGQMEVQSTLGQGTCFTLR
LPLAGTTPLASHELKQLER