Protein Info for AO353_02400 in Pseudomonas fluorescens FW300-N2E3

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 PF00392: GntR" amino acids 11 to 71 (61 residues), 59.3 bits, see alignment E=2.3e-20 TIGR03337: phosphonate utilization transcriptional regulator PhnR" amino acids 11 to 236 (226 residues), 300.1 bits, see alignment E=5.5e-94 PF07702: UTRA" amino acids 92 to 230 (139 residues), 132.7 bits, see alignment E=8.7e-43

Best Hits

Swiss-Prot: 46% identical to PHNR_SALCH: Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons (phnR) from Salmonella choleraesuis (strain SC-B67)

KEGG orthology group: None (inferred from 97% identity to pfo:Pfl01_1687)

Predicted SEED Role

"2-aminoethylphosphonate uptake and metabolism regulator" in subsystem Phosphonate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VJB4 at UniProt or InterPro

Protein Sequence (237 amino acids)

>AO353_02400 MFS transporter (Pseudomonas fluorescens FW300-N2E3)
MREEATKAVTAIGQVLQEQIDHGLLAPASKLPAERKLSELFGTTRITVREALLQLEAQGQ
IYREERRGWFVSPPRLAYNLMQRSHFHAMVSAQGRVPSTEVISARLQPASAAVCAWLQLP
ALSSVIQICRSRRIDGRLVLYVEHYLNPQFFPGILAFDLNQSITELYARHYDLHYGRVRF
EIVPTALSVDAAAALRVSVGSPGLRIARVNYDQHGRLIDCDLEFWRHDAIHVGVDVV