Protein Info for AO353_02390 in Pseudomonas fluorescens FW300-N2E3

Annotation: aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 PF02127: Peptidase_M18" amino acids 12 to 423 (412 residues), 462.2 bits, see alignment E=1.7e-142

Best Hits

Swiss-Prot: 97% identical to APEB_PSEPF: Probable M18 family aminopeptidase 2 (apeB) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K01267, aspartyl aminopeptidase [EC: 3.4.11.21] (inferred from 96% identity to pfl:PFL_4383)

Predicted SEED Role

"Aspartyl aminopeptidase"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N7GZC4 at UniProt or InterPro

Protein Sequence (429 amino acids)

>AO353_02390 aminopeptidase (Pseudomonas fluorescens FW300-N2E3)
MREELNQGLIDFLKASPTPFHATASLVQRLEAAGYQRLDEREPWATEANGRYYVTRNDSS
IVAIKMGRNSPLYDGIRLVGAHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDR
DLSLAGRVTFRRDGKVESQLIDFKTPIATIPNLAIHLNREANMGWAINAQTELPPILAQF
AGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAVIGLHGDFIAGARLDNLLS
CYAGLQALLTAETDETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGDEFVRTIQK
SLLVSADNAHGVHPNYADKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEE
VPVQSFVVRSDMGCGSTIGPITASHLGVRTVDIGLPTFAMHSIRELCGSHDLAHLVKVLS
AFYASRELP