Protein Info for AO353_00620 in Pseudomonas fluorescens FW300-N2E3

Annotation: cytochrome C oxidase Cbb3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 34 to 319 (286 residues), 256 bits, see alignment E=2.3e-80 PF14715: FixP_N" amino acids 37 to 83 (47 residues), 83.5 bits, see alignment 1e-27 PF13442: Cytochrome_CBB3" amino acids 146 to 219 (74 residues), 46.3 bits, see alignment E=6.6e-16 amino acids 236 to 312 (77 residues), 42.9 bits, see alignment E=7.7e-15 PF00034: Cytochrom_C" amino acids 149 to 221 (73 residues), 31.3 bits, see alignment E=6.6e-11 amino acids 238 to 284 (47 residues), 31.8 bits, see alignment 4.5e-11

Best Hits

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 94% identity to pfo:Pfl01_1820)

MetaCyc: 88% identical to cbb3-2 cytochrome c oxidase subunit P (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WCG0 at UniProt or InterPro

Protein Sequence (325 amino acids)

>AO353_00620 cytochrome C oxidase Cbb3 (Pseudomonas fluorescens FW300-N2E3)
MTTFWSLYVTVLSLGTIFALTWLLLSTRKGQRAEQTDETVGHAFDGIEEYDNPLPKWWFM
LFVGTIIFALGYLVLYPGLGNWKGLLPGYGYLDNEKQTAFANGQSGWTGVHEWEKEMAKS
DAKFGPIFAKFAAMPIEEVAKDPQALKMGGRLFASNCSVCHGSDAKGAYGFPNLTDEDWR
WGGEPQTIKTTIMGGRHAMMPAWGEVIGEQGVSDVAAFVLTNLDGRKLPEGAKADPVAGQ
KIFAANCVACHGPEGKGTPAMGAPNLTHPAAFIYGSSFAQLQQTIRYGRQGQMPAQEQLQ
GNDKVHLLAAYVYSLSHGEKAADAE