Protein Info for AO353_00535 in Pseudomonas fluorescens FW300-N2E3

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 596 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details transmembrane" amino acids 66 to 85 (20 residues), see Phobius details amino acids 142 to 159 (18 residues), see Phobius details amino acids 165 to 183 (19 residues), see Phobius details amino acids 246 to 266 (21 residues), see Phobius details amino acids 278 to 298 (21 residues), see Phobius details TIGR02204: ABC transporter, permease/ATP-binding protein" amino acids 6 to 581 (576 residues), 880.7 bits, see alignment E=2.5e-269 PF00664: ABC_membrane" amino acids 27 to 292 (266 residues), 179 bits, see alignment E=1.7e-56 PF00005: ABC_tran" amino acids 362 to 510 (149 residues), 102.4 bits, see alignment E=3.3e-33

Best Hits

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 90% identity to pfo:Pfl01_3884)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WS32 at UniProt or InterPro

Protein Sequence (596 amino acids)

>AO353_00535 ABC transporter ATP-binding protein (Pseudomonas fluorescens FW300-N2E3)
MLSARHRRAIRLASRFVAPYRWQALGALLALIVTAGITLSMGQGIRLLVDQGFMTQSPQL
LNQSIGVFMLLVLGLAIGTFMRFYLVSWIGERCVADIRQQVFNHLIYLHPGFYENNRSSE
IQSRLTADTTLLQSVIGSSLSLFLRNLLMVIGGVVLLFITNPKLTSIVVVTLPLVIAPIL
IFGRRVRRLSRLSQDRIADIGSYVSESLGQIKTVQAYNHQVQDEQRFAVTVEEAFDTARK
RIVQRAWLITLVIMLVLGAVAVMLWVGGMDVIAGRISAGELAAFVFYSLIVGSAFGTLSE
VIGELQRAAGAAERIAELLRSENIIQPPVSGQVTLPDRVRGDLLLQDLRFSYPSRPESYA
IDGLSLAIKAGETLALVGPSGAGKSTVYDLLLRFYDPIAGRILLDGVPLTQLDPMDLRRC
FALVSQNPALFFGSIEENIRYGKPSATLAQVQEAAKIAYAHDFIEKMPDGYQTHLGDGGL
GLSGGQRQRLAIARALLVDAPILLLDEATSALDAQSEHLIQQALPSLMKNRTTLVIAHRL
ATVKNADRIAVMDQGKLIAVGTHQELLASNALYARLAALQFVGAAEEGDLFDGATK