Protein Info for AO353_00005 in Pseudomonas fluorescens FW300-N2E3

Annotation: isoprenylcysteine carboxyl methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 transmembrane" amino acids 7 to 32 (26 residues), see Phobius details amino acids 38 to 59 (22 residues), see Phobius details amino acids 71 to 90 (20 residues), see Phobius details amino acids 102 to 123 (22 residues), see Phobius details amino acids 157 to 186 (30 residues), see Phobius details PF04191: PEMT" amino acids 104 to 202 (99 residues), 58.2 bits, see alignment E=1.6e-19 PF04140: ICMT" amino acids 109 to 196 (88 residues), 57.1 bits, see alignment E=3.1e-19 PF01222: ERG4_ERG24" amino acids 134 to 219 (86 residues), 28.5 bits, see alignment E=1e-10

Best Hits

KEGG orthology group: None (inferred from 68% identity to bac:BamMC406_5331)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VZI0 at UniProt or InterPro

Protein Sequence (219 amino acids)

>AO353_00005 isoprenylcysteine carboxyl methyltransferase (Pseudomonas fluorescens FW300-N2E3)
MKISLKLAVFSIAAVLVYLGLAILGLGGFAAFLSHPALVIIALATLVMVGASLLTEANLN
SGVREDRANRWVLPVFGVIGVLSAFIPAYTDRMDFWTFDGEGIRWVGAALFIAGGALRIW
PVFVLGKRFSGLVAIQPGHTLVTDGIYRRLRNPSYLGLLINALGWALAFRSSVGIVLVLL
LLPALIARINAEEDLLRSEFGAEYDAYCAKTWRLIPGLY