Protein Info for ABZR87_RS23640 in Ralstonia sp. UNC404CL21Col

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 PF14361: RsbRD_N" amino acids 3 to 111 (109 residues), 35.2 bits, see alignment E=2.5e-12 PF00512: HisKA" amino acids 152 to 214 (63 residues), 42.2 bits, see alignment E=1e-14 PF02518: HATPase_c" amino acids 262 to 369 (108 residues), 76.8 bits, see alignment E=2.6e-25

Best Hits

KEGG orthology group: None (inferred from 58% identity to bgl:bglu_1g14850)

Predicted SEED Role

"Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)" in subsystem Potassium homeostasis (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>ABZR87_RS23640 sensor histidine kinase (Ralstonia sp. UNC404CL21Col)
MTLSDFIEANLAALLDDWTEYARTIISGRASLSESQLRNSARDLLGRIAADMRERQTPEQ
QRAKSRGDRAPSESGFNEAAHEHADDRLSHGFDIDDVVAEYRALRASVLHRWQQFAQSDP
SAFQEMIRFNEAIDQMLAESVRQRAQQTERMRDLFAGVLAHDLRSPLGAILASAETLLHD
DGLSSRSVRAVAFIQRGAMRVQQMIDDLLIFTRTRLGDFLPTSFSSQDMGRLCSDAIDEV
CASYPDAQIDLRLAGELRGKWDGSRIGQLLVNLLANAVRYGTGRVGIEAAGRDGQMTIAV
SNEGNPIPPSAFPTLFDPLTRAQRPDQTGSAAGIGLGLYICRCIVQAHHGTIDVQSSEHG
TTFTVRIPLLVTA