Protein Info for ABZR87_RS23620 in Ralstonia sp. UNC404CL21Col

Annotation: winged helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF12840: HTH_20" amino acids 14 to 64 (51 residues), 41.5 bits, see alignment E=1e-14

Best Hits

Swiss-Prot: 43% identical to YDFF_BACSU: Uncharacterized HTH-type transcriptional regulator YdfF (ydfF) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 90% identity to rpi:Rpic_3818)

Predicted SEED Role

"Transcriptional regulator, ArsR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>ABZR87_RS23620 winged helix-turn-helix domain-containing protein (Ralstonia sp. UNC404CL21Col)
MSHLNSFSGTAFLIADPARAAMLTALLDGRALPAGELAHAAGVTAQTASTHLAKLLDGGL
LVVETEGRHKYFRLAGAHVAQALEHLAAITPAAAVRRATPSPKARELGFCRCCYDHLAGQ
VGVAVTQALQSRGYLLPMPDKQYEITPAGVMWFGDVGLDVRTIRPTRRGLARQCLDWTER
THHLAGPLGVQFLRRLCDVGWMLRARDSRAVLVTPKGWQELRQRLGVDEASVRSQAAHRH
A