Protein Info for ABZR87_RS23375 in Ralstonia sp. UNC404CL21Col

Annotation: CheR family methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 PF01739: CheR" amino acids 82 to 253 (172 residues), 147 bits, see alignment E=7.4e-47 PF08241: Methyltransf_11" amino acids 182 to 247 (66 residues), 21.6 bits, see alignment E=4.2e-08

Best Hits

KEGG orthology group: K13486, chemotaxis protein methyltransferase WspC (inferred from 66% identity to rso:RS02206)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (484 amino acids)

>ABZR87_RS23375 CheR family methyltransferase (Ralstonia sp. UNC404CL21Col)
MVAVDPRFEAWLSHETGIDAPSLGTNALERAVLDRTRAMLAARGMPDTVDAVDAAALDAY
WLRLNTAPDERQALIEALVVPETWFFRDREAFVTLARVVGEKLAREPMRVLRILSAPCST
GEEPYSAAMALLDAGIDPARFTIDAIDISTRAIEQARRAVYGRNAFRGHPLTFRDRHFTE
AAGGWQLSDTVRGLVRFAQGNLSDAPADDTRYDFIFCRNVLIYFHRDAQDQAIRRLDSQL
AEDGMIFVGPAETGLMMRHAMTSARIPLAFAFQRTAAGETGARASLPFRLPLPPETAASA
VGLPGVALPSVPVRPVAARVPAPSRPSPAPSLATRPLAHPLARPVLRTIPEIEAVLGEPP
TVAEARRLADAGNLDEAERVALEIANLRAPEADTFYLLGLIADARGRHADAGDFYRKALY
LEPAHYEALTHLAALLDVAGDTVAARQLMLRAERALARQGKTPSASSESGTPEHTRGTHG
ARRP