Protein Info for ABZR87_RS22955 in Ralstonia sp. UNC404CL21Col

Annotation: cytochrome c oxidase subunit 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00510: COX3
  • amino acids 94 to 185 (92 residues), 26.8 bits, E=2.3e-10

Best Hits

KEGG orthology group: K02276, cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 78% identity to rso:RSp1566)

Predicted SEED Role

"Alternative cytochrome c oxidase polypeptide CoxO (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

• aerobic respiration I (cytochrome c) (3/4 steps found)
• arsenite to oxygen electron transfer (1/2 steps found)
• aerobic respiration II (cytochrome c) (yeast) (2/4 steps found)
• arsenite to oxygen electron transfer (via azurin) (1/3 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Protein Sequence (203 amino acids)

>ABZR87_RS22955 cytochrome c oxidase subunit 3 (Ralstonia sp. UNC404CL21Col)
MTTLPRHFAPDTSPALPPHAGRIGLRVFMAVVTTLFLLLILAYAMRMREPDWMPVPHPAL
LWWNTGVLALASVAMEGTRRTDARRTPWLLAGGALAALFVFGQWAAWQQLSATGQGVAVN
PSNSFLYVFTGLHAAHVVGGLVVWAVTVARLHRNADRTRLAVSLCATYWHFLLAVWLVLL
AAMWWITPAFVSAICGPLYGATP