Protein Info for ABZR87_RS22895 in Ralstonia sp. UNC404CL21Col

Annotation: S53 family serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 567 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF09286: Pro-kuma_activ" amino acids 51 to 184 (134 residues), 109.8 bits, see alignment E=1.4e-35 PF00082: Peptidase_S8" amino acids 301 to 537 (237 residues), 49.1 bits, see alignment E=5.4e-17

Best Hits

Swiss-Prot: 66% identical to PICP_PSESR: Pseudomonalisin (pcp) from Pseudomonas sp. (strain 101)

KEGG orthology group: K05998, pseudomonalisin [EC: 3.4.21.100] (inferred from 79% identity to bmu:Bmul_4660)

Predicted SEED Role

"Xanthomonapepsin precursor (EC 3.4.21.101)" (EC 3.4.21.101)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.100 or 3.4.21.101

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (567 amino acids)

>ABZR87_RS22895 S53 family serine peptidase (Ralstonia sp. UNC404CL21Col)
MQRFSTLCRHLAYAWPLVFAAGPLHAATDWVDTHTKAFVTGPQLMARGAANEVAPGQTTD
VLVSLKLRNEATLKALAHEVNDPHSPRYRKYLTSEQFLADHAPTQAQVDAVVGYLRQNGF
IDIDVAPNRLLVSARGTAGTVKAAFNTPLVHYQLAGRSGFANSGKAQVPRALGGIVGSVL
GLQNVARARPLLRVGDVAEARTLAAGTATGHYPKEFPALYGATGVPTAAGTTVGVITIGG
VSQTLRDLRTFTSNNGYAAVSTTTIKTNGTSGNYTDDQEGQGEWNLDSQSIVGAAGGAVG
KLAFYMADLNAPGNTGLTKAFNKAVTDNTAKIINVSLGWCESDASADGTLDAEEAIFTTA
AAQGQTFSVSSGDEGVYECNNRGYPDGGNYSVSWPASSPHVLAIGGTTLYTSGSSFASET
VWNEGLDGNGKLWATGGGISQILPAPSWQGGNARLLPDVSFDAAQSTGAYIYNYGQLQQI
GGTSLASPIFVGFWARLLAANGNLGFPAARLYSAIPANASLLRYDVVSGNNGYQGYGYSA
AKGWDYPTGWGSLNIGALNQLIKSGGF