Protein Info for ABZR87_RS22805 in Ralstonia sp. UNC404CL21Col

Annotation: phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 PF00563: EAL" amino acids 27 to 247 (221 residues), 136.6 bits, see alignment E=9.5e-44 PF00990: GGDEF" amino acids 423 to 515 (93 residues), 51.4 bits, see alignment E=1.1e-17 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 436 to 514 (79 residues), 45.7 bits, see alignment E=3e-16

Best Hits

KEGG orthology group: None (inferred from 91% identity to rpf:Rpic12D_3777)

Predicted SEED Role

"FOG: EAL domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (604 amino acids)

>ABZR87_RS22805 phosphodiesterase (Ralstonia sp. UNC404CL21Col)
MSDLASAANVMTFSPLPLPAGIAPEMLRTVFQPIFRLSTTEVLGYEALLRGPVGSAMESP
AALFAAASDTAGTIALETTAARLAIANFSAMRLPGKLFLNFSAQGVRQLLQDHARLLHAI
ADHDLHPSRIVIELTEQTPIDDLASFADALSVARDFGLQCALDDFGTGNANLNLLIELTP
DFIKLDKYFLRDIAKHPAKLDMARTLQQTLKGGATSIIAEGLETEDELGVVRDLGIRFGQ
GFFLARPQDKPASDMSSQAARVLQSSQIAVFPQAVRVGWRAITASKLLRVAPTLPLRSSN
DDVLHLFNRHPDLHAVALLDEDERPLALIARRAFIDRYAMPYHRELYGKKPALAFANRQP
VLVEKSASLEDMSALLMSEDQRYLTDGFIITEHGRYLGLGTGEELVRTVTEIRIEAARYA
NPLTFLPGNIPLNLHIERLLEAHAEFYACYVDLNHFKPFNDQYGYWQGDEMLKMAAAVLA
TACEPTRDFLGHVGGDDFLILFQSADWQARITQAMAAFNANALAMYTPPDRAAGGIHAED
RKGLPAFFRFVTMAVGALHVHPGAAHNSDDIGTAAALAKRRAKQSDNGFYLEAMRPSHSM
RAMA