Protein Info for ABZR87_RS22355 in Ralstonia sp. UNC404CL21Col

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 747 transmembrane" amino acids 33 to 53 (21 residues), see Phobius details TIGR01409: Tat (twin-arginine translocation) pathway signal sequence" amino acids 28 to 52 (25 residues), 20.7 bits, see alignment (E = 2e-08) PF20256: MoCoBD_2" amino acids 41 to 206 (166 residues), 45.7 bits, see alignment E=6.6e-16 amino acids 619 to 699 (81 residues), 36.2 bits, see alignment E=5.2e-13 PF02738: MoCoBD_1" amino acids 337 to 575 (239 residues), 96.3 bits, see alignment E=1.7e-31

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 96% identity to rpi:Rpic_4804)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (747 amino acids)

>ABZR87_RS22355 xanthine dehydrogenase family protein molybdopterin-binding subunit (Ralstonia sp. UNC404CL21Col)
MRIRNLEALAGGGAQHQPASAEAGSATLDRRSFLKLTTLAGGGLALGVVPVLAGAQDAKA
KPPSPPQAFIIIAPDNTVTVAVNRLEFGQGVHTALPMALAEELDVDWRNVRGMLAPAGDP
YKDPGFGIQMTGGSTALNHSFQQYRELGGRARAMLISAAAERWKVDPSTCRTANGVVTSG
SHRATYGELAQAAMALPVPAQVTLKNPSQFRIVGKPTPRLDARAKLDSSLKFGLDTRLPN
MKVAVLARPPRFGGKVAKYDAAAAKAVKGVVDVLQIPTDRGGTGVAVIADGYWPAKQGRD
ALQVTWEDAGSTVSTPALMAEYKKLAGQPGTVAKAADMSAIQSAATRIQADYEFPYLAHA
PMEPLNCTIDLQKDGGKTTGAKVWVGSQFQTIDQGAIAKVLGVSPEKIELNTMMAGGGFG
RRAITTSDYVVEAANVAKAYAAAGHNGPVKVIWSREDDIRGGYYRPMHLHRVNVGVDNSG
KVVGWDHVIVGQSILKGTPFEAFMVKNGVDETMVEGVIENDYGFPMQLTVHHPDVNVPVL
WWRSVGHTHTAYVMETMVDEVAHAAKQDPVAFRLARFTGKEHERHRAALQLAVDKSGYGK
RKLPKGQAWGVAVHASFESVVAYVVEVSVDQGKPRVHRVTAGVHANRVVNPMGAEAQIQG
ACVFGLAMIQPGFAIDIENGATKNSNFTDFPPVRMPDAPPVNVFFVPSEDNPTGLGEPGT
PPIAPAVANALFTLTGKRQRKLPFDTV