Protein Info for ABZR87_RS21745 in Ralstonia sp. UNC404CL21Col

Annotation: M20 family peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF04389: Peptidase_M28" amino acids 117 to 229 (113 residues), 28.7 bits, see alignment E=1.6e-10 PF01546: Peptidase_M20" amino acids 130 to 503 (374 residues), 117.1 bits, see alignment E=1.6e-37 PF07687: M20_dimer" amino acids 252 to 402 (151 residues), 68.8 bits, see alignment E=5.5e-23

Best Hits

KEGG orthology group: K13049, carboxypeptidase PM20D1 [EC: 3.4.17.-] (inferred from 93% identity to rpf:Rpic12D_3627)

Predicted SEED Role

"macromolecule metabolism; macromolecule degradation; degradation of proteins, peptides, glycopeptides"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.17.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (508 amino acids)

>ABZR87_RS21745 M20 family peptidase (Ralstonia sp. UNC404CL21Col)
MHASFKRRRTRTGRVVGRLLLAIAVILVGLAAVVGVNTWRHDSRQLDVPAVTPVAVDGPA
AAAHLAEAVRARTVSSAADAQLNADQFRQLHAMLAARYPQAHAVLQREQVGDFALLYTWK
GTDPSLKPIMLMAHQDVVPIAPGTEGDWTQPPFDGVVKDGMVWGRGAWDDKGNLISQMEA
IELLAASGFKPRRTIHLAFGADEEVGGDRGAKQIAALLKSRGERLDFVIDEGLLITEGVL
PGLTKPAALIGVAEKGFLSVQLKVGATPGHSSMPPPHGQSAIAMMSATLKRLDDDQLPAG
IRGVAQEMFATLAPEMQGFSRVALSNLWLFGPLVQKQLEASGSSNAMLRTTTALTIVQAG
NKDNVLPGRAEATVNFRLLPGDTIASVTAHVEDAAKAAAPHGKFELSRLPGSSEASPVSP
TQSASYQLINKTVRELFPGTVVAPGLMIGATDSRHMIEIADHVYRFSPVRAKPEDLPRFH
GTNERITEANLVELIRFYHRLVQQAAGA