Protein Info for ABZR87_RS21555 in Ralstonia sp. UNC404CL21Col

Annotation: aspartate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 36 to 452 (417 residues), 292.8 bits, E=1.8e-91

Best Hits

Swiss-Prot: 39% identical to Y4UB_SINFN: Uncharacterized aminotransferase y4uB (NGR_a01380) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 93% identity to rsl:RPSI07_mp1042)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

• biotin biosynthesis I (13/15 steps found)
• biotin biosynthesis from 8-amino-7-oxononanoate I (4/4 steps found)

KEGG Metabolic Maps

• Biotin metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.1.62

Protein Sequence (466 amino acids)

>ABZR87_RS21555 aspartate aminotransferase family protein (Ralstonia sp. UNC404CL21Col)
MTQLTDLPQLASLDAIDRAHLIHPVAAWRTHEQRGPTVLTSGRGAWLTDAHGNELLDAFA
GLWCVNVGYGQESVVQAAAEQMRRLPYATGYFHFSSEPAIRLADKLVQITPRSLNHVYLT
LGGSEAVDAAVRFIVQYFNAVGKPTKKHFISLERGYHGSSSTGAGLTALPAFHRDFDLPL
PTQHYIPSPNPYRAANPADAQGIIDASVAALRAKVAALGADNVAAFFCEPIQGSGGVIVP
PKGWLKAMRDATRELGILFVVDEVITGFGRTGPMFACDAEGVDPDIMTMAKGLTAGYVPM
GATLISDQLYAGIADGAPAGVPIGHGATYSAHPVSAAVALEVLRLYEEGGILANGQRGAT
SFAAGLDGLLTHPLVGDARHRGLLGALELVSNKATKRGFDAALGLPNLIATAAYGNGLVF
RAFGDNILGFAPALTYTEDEFAQLFARLKKTLDDVLAMPAVRAALA