Protein Info for ABZR87_RS21240 in Ralstonia sp. UNC404CL21Col

Annotation: 1,2-phenylacetyl-CoA epoxidase subunit PaaE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 TIGR02160: phenylacetate-CoA oxygenase/reductase, PaaK subunit" amino acids 5 to 364 (360 residues), 454.6 bits, see alignment E=9.3e-141 PF00970: FAD_binding_6" amino acids 9 to 113 (105 residues), 39.6 bits, see alignment E=8.5e-14 PF00175: NAD_binding_1" amino acids 128 to 235 (108 residues), 58.5 bits, see alignment E=1.5e-19 PF00111: Fer2" amino acids 282 to 354 (73 residues), 58.1 bits, see alignment E=1e-19

Best Hits

KEGG orthology group: K02613, phenylacetic acid degradation NADH oxidoreductase (inferred from 92% identity to rso:RSp0608)

Predicted SEED Role

"Phenylacetate-CoA oxygenase/reductase, PaaK subunit"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (366 amino acids)

>ABZR87_RS21240 1,2-phenylacetyl-CoA epoxidase subunit PaaE (Ralstonia sp. UNC404CL21Col)
MTPQFHPLRVAEVRGETADTISVRFDVPNDLRDAYRFTQGQFLTLRVPPGQLPGHEELRR
SYSICCAVQDYDAHGELRVAVKRVDAGVFSNHLHDRIRVGQTLDVLPPDGRFYVPLAAES
ARHYVAFAAGSGITPILSLIKTTLAAEPQSRFTLVYGNRSIDSIIFGEALEDLKDRYLDR
FALYHVLSRQAQEIALFNGRLDGAKVHAFLDTLIPPDDIDAAFICGPSTMIDAVEAALLE
RGVPRERVHAERFGVPVGDATTAAKPRKHAAVAGDVALTVVLDGKSHEVPMAGDAKVLDS
ALSAGLDLPYACKGGVCCTCRAKVLEGRVEMEKNFTLEDWEIQQGFVLTCQARPLTQRVV
VSYDER