Protein Info for ABZR87_RS21130 in Ralstonia sp. UNC404CL21Col

Annotation: RNA polymerase sigma factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 PF04542: Sigma70_r2" amino acids 27 to 83 (57 residues), 35.6 bits, see alignment 1.3e-12 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 33 to 176 (144 residues), 45.1 bits, see alignment E=4.1e-16 PF08281: Sigma70_r4_2" amino acids 125 to 175 (51 residues), 38.9 bits, see alignment 1.1e-13 PF20239: DUF6596" amino acids 193 to 293 (101 residues), 126.2 bits, see alignment E=1.2e-40

Best Hits

KEGG orthology group: None (inferred from 85% identity to rso:RS03731)

Predicted SEED Role

"RNA polymerase sigma-70 factor, ECF subfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>ABZR87_RS21130 RNA polymerase sigma factor (Ralstonia sp. UNC404CL21Col)
MADSTQEALAIHRTIDAVWRIESARIIAGLARLLRDVGLAEELAQDALVAALEQWPASGI
PDNPAAWLTATAKHRAIDRLRHHTLAEQKHARLAIELEIEHELAQADAEAARDEAIGDDL
LRLVFISCHPALPHEGRVALTLRLLGGLTTDEIARAFLVPEPTVAQRIVRAKKTLAAARV
PFELPEPDALPERLSAVLQVIYLVFNEGYAATAGDDWTRPTLCEEAQRLGRILAGLMPGE
PEVHGLLALMELQASRLRARVGPDGRPILLMEQDRSRWDYLLIQRGFAALAQAEARGRGL
GPYGLQAAIAACHASARTAEQTDWTRIAALYDALAQLTPSPVVELNRAVAVAMAYGPQAG
LEIVDTLLAEPALRSYHLLPSVRADFLARLHRMEEARAEYERAAALTHNRQERALLLERA
AGCNARG