Protein Info for ABZR87_RS21075 in Ralstonia sp. UNC404CL21Col

Annotation: MerR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 transmembrane" amino acids 100 to 117 (18 residues), see Phobius details PF13411: MerR_1" amino acids 15 to 79 (65 residues), 57.6 bits, see alignment E=1.1e-19 PF00376: MerR" amino acids 18 to 53 (36 residues), 30.5 bits, see alignment 2.6e-11

Best Hits

Predicted SEED Role

"Transcriptional regulator, MerR family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (328 amino acids)

>ABZR87_RS21075 MerR family transcriptional regulator (Ralstonia sp. UNC404CL21Col)
METHVPPEDNAAPMYRSGTAARMAKMPVSTLRVWEQRYGVISPAKSESGQRLYSSEDVRR
LALLRALVNQGHAIGAIAHADSTELQQLLEASVTVEAPAPAPSTAAISLAVCGALLAERV
RRRKSTLASLGIEPVIELPALDGEAHVEPPPRTDALVVEAASLHPETAEAVLAAARRCGA
SAVGVIYSFGTVRATDMLRAAGVRLYREPNAQGELDQVLQELAQLVRVDAVYGKLEPLRR
NARRFTDRQLEIFANASQTLACECPRHLVGLIRQLDAFERFSDGCAVRSSLDEQLHRYLG
DVANRARLMLEDAMEFAIRAETLHPPAG