Protein Info for ABZR87_RS20910 in Ralstonia sp. UNC404CL21Col

Annotation: efflux RND transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 42 to 362 (321 residues), 220.5 bits, see alignment E=1.4e-69 PF16576: HlyD_D23" amino acids 67 to 268 (202 residues), 53.4 bits, see alignment E=4.3e-18 PF13533: Biotin_lipoyl_2" amino acids 69 to 115 (47 residues), 27.6 bits, see alignment 4e-10 PF13437: HlyD_3" amino acids 179 to 270 (92 residues), 49.3 bits, see alignment E=1.5e-16

Best Hits

KEGG orthology group: None (inferred from 83% identity to rpi:Rpic_4544)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (385 amino acids)

>ABZR87_RS20910 efflux RND transporter periplasmic adaptor subunit (Ralstonia sp. UNC404CL21Col)
MTGQRVWMGALAVLLAGALAACGKSAPENEKKQTPAKPALAVNVAHLAQQVWPRVATASG
AVQPWQEASIGAEVSGLKLAEVLVNVGDVVKQGQLLARLSDETVRADVAAQRASLAEAEA
SAAQAAGEAHRAHELDKSGAISQQDLIQYDTQAKTAAAKLAAARAQFESQQLRLRYTRVV
APDDGVISARTATVGAVVSSGTELFKLIRKNRLEWRAEMHGDVLPRIQPGQAARVRRMDG
GVVNGRVRQVAPTVDANTRNGLIYVDLPPEAATSGVKAGMYLSGDVLLGDAPAATLPETA
VFSRDGYDYVMVIGQQGRVRQTKVTVGRRQAGNVEIVQGIGANDGVVAAGAAFLSDGDVV
RVAAAGATSAPAVPAAAAPAAGAKP