Protein Info for ABZR87_RS20905 in Ralstonia sp. UNC404CL21Col

Annotation: efflux RND transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1031 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 331 to 351 (21 residues), see Phobius details amino acids 358 to 378 (21 residues), see Phobius details amino acids 384 to 408 (25 residues), see Phobius details amino acids 429 to 449 (21 residues), see Phobius details amino acids 461 to 480 (20 residues), see Phobius details amino acids 520 to 541 (22 residues), see Phobius details amino acids 842 to 864 (23 residues), see Phobius details amino acids 871 to 893 (23 residues), see Phobius details amino acids 899 to 923 (25 residues), see Phobius details amino acids 944 to 963 (20 residues), see Phobius details amino acids 975 to 998 (24 residues), see Phobius details PF00873: ACR_tran" amino acids 4 to 999 (996 residues), 806.5 bits, see alignment E=5e-246 PF03176: MMPL" amino acids 256 to 487 (232 residues), 31.3 bits, see alignment E=1.6e-11 PF02355: SecD_SecF" amino acids 330 to 477 (148 residues), 28.3 bits, see alignment E=1.7e-10

Best Hits

KEGG orthology group: None (inferred from 93% identity to rpi:Rpic_4543)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1031 amino acids)

>ABZR87_RS20905 efflux RND transporter permease subunit (Ralstonia sp. UNC404CL21Col)
MNFSAWAIRKPIPSILLFILITVAGLVSFKMLSIQNFPDIDFPAVSVTASLPGATPTQME
TEVTRKIEDSIASIGAIKHITSTINDGSSTTMVEFQLEKDVQEAVNDVRDAVSRIRAQLP
SDVQEPVISRVTFASLPVLTYAVEASDMDAEDLSWFVDNTVNKRLLSVHGVAKVTRQGGV
DREVRVQLDPVRLQALNVSAADISAQVRGMQQEAPGGRGNIGGQEQAVRTLGTVKSAREL
AQMDIPLSDGRRIRLSDVADVRDTAAEPRQMALFDGKAVVSFQVFRSRGASEISVAKGVR
EALAALQAERPNVHVTEVYNMVKPVSDAYTASMHALYEGAILAVIVVWLFLRDWRATFVS
AVALPLSIIPTFAAMQLLDFTLNGITLLALTLVVGILVDDAIVEVENIVRHLRNGKKPLE
AAMEAAQEIGLAVVATSLTLVAVFLPTAFMGGISGKFFKQFGWTASLAVLASLLVARLLT
PMMAAYMLKPQDEPNRDSWIMTRYLQAARWCLVHPWKTGGMAAAFFVVSVAIIGLIPATF
LPPEDWAQLQMTVESPPGSTIAQTRDNTERVRKIVMQHKEVRHVYTAIGSGVMAGVPGSS
GGEVRNGTLTISLTDRHDRHVKQQDVQRQLREMLEGVPGVRISFGAVGSGEQLQVVLTGD
DPATLQQAARDVMRDLRTVPGLGAVTSSASLLRPEIVIRPDFARAAQQGVTAAAIGQAVR
VATAGDYDVNLPKLNLPERQVYIRVELDPKARNQIDTIRQLRVPGRNGAVPLENIADISI
GSGPAQIDRYDRSRNVTISVGLEGRALGDTNMAVEALPSIKNLPPGVRRIASGDVEGMQE
LFSSFFLAMFAGVLCVYAVLVLLFHDFTQPVTILAALPLSVGGAFGLLALFGFSLSLPAL
IGLLMLMGIVTKNSILLVEYAIVARRDLGMSRTEAIIDACHKRARPIVMTTVAMTAGMVP
MALGLEGDAGFRAPMAVAVIGGLLTSTLLSLLVVPVVFEKADDFKEWALRKFRGVRHHGH
RAEAASEYGPR