Protein Info for ABZR87_RS20830 in Ralstonia sp. UNC404CL21Col

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00106: adh_short" amino acids 13 to 190 (178 residues), 152 bits, see alignment E=3e-48 PF01370: Epimerase" amino acids 16 to 185 (170 residues), 29.5 bits, see alignment E=1e-10 PF13561: adh_short_C2" amino acids 20 to 251 (232 residues), 204.3 bits, see alignment E=4.5e-64

Best Hits

Swiss-Prot: 56% identical to BDH2_MOUSE: 3-hydroxybutyrate dehydrogenase type 2 (Bdh2) from Mus musculus

KEGG orthology group: None (inferred from 75% identity to bxe:Bxe_B2957)

Predicted SEED Role

"2-keto-3-deoxy-L-fuconate dehydrogenase" in subsystem L-fucose utilization temp

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>ABZR87_RS20830 SDR family oxidoreductase (Ralstonia sp. UNC404CL21Col)
MSGAAFPGRLAGKTALVTAAAQGIGRACAERFAREGARVIATDLRIDALNDVPFEVHRLD
VRDTGQVNALAAELGGIDILFNCAGFVHAGSVLECDEDAWDFSFDLNVKSMYRTLRAFLP
GMLERGGGSVINMSSAASSIKGVPNRFVYGASKAAVIGLTKSVAADFVARGIRCNAICPG
TVVSPSLAQRIDEQARTQGKPRAEVEAAFVARQPMGRLGQPEEIAALAAYLASDEAAFTT
GQVHLIDGGWSN