Protein Info for ABZR87_RS20305 in Ralstonia sp. UNC404CL21Col

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 48 to 69 (22 residues), see Phobius details amino acids 76 to 101 (26 residues), see Phobius details amino acids 137 to 158 (22 residues), see Phobius details amino acids 165 to 185 (21 residues), see Phobius details amino acids 267 to 289 (23 residues), see Phobius details amino acids 303 to 322 (20 residues), see Phobius details amino acids 328 to 349 (22 residues), see Phobius details amino acids 361 to 383 (23 residues), see Phobius details amino acids 392 to 412 (21 residues), see Phobius details PF07690: MFS_1" amino acids 16 to 297 (282 residues), 168.6 bits, see alignment E=9.3e-54 amino acids 302 to 424 (123 residues), 49.6 bits, see alignment E=1.4e-17

Best Hits

Swiss-Prot: 56% identical to EXUT_ECO57: Hexuronate transporter (exuT) from Escherichia coli O157:H7

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 98% identity to rpi:Rpic_4445)

MetaCyc: 56% identical to hexuronate transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-123; TRANS-RXN-35

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (433 amino acids)

>ABZR87_RS20305 MFS transporter (Ralstonia sp. UNC404CL21Col)
MKPIKGLRWWIIGLVLSGLIMNYLARNALAVAAPEVNKVLNISTQQYGYIVAAFQAAYMV
MQPVAGYVLDVLGTKLGFALFAAAWSVVCLLHSTAGGWLSLAAFRAMLGMTEAAGFPSAL
RATAEWFPAKERSIATGWFNIGSSVGAVVAPPLVVWCILHGNWRFAFAVIGGMGLVWSVL
WFLLYRVPAKHHRLSAEEREYIRAGQETPDDNADAPKPSWGKIVSGRRFWGIAIPRFLSE
PAWQTFNYWIPLYMATERHMNLKEIALFAWLPFLAADVGCVLGGYLAPWFQKRFSVSLVT
SRKLVMVTGCLCMIGPACIGLATSPYTAIALFCVGGFAHQTLSGALYTLTSDMFGKHEVG
TAVGLAGMSGYMGGMLFSLAVGTLATTIGYNPLFVALAVFDIVAAILVWTMLNDKQARPV
PMQPGGTAPSTAT