Protein Info for ABZR87_RS20030 in Ralstonia sp. UNC404CL21Col

Annotation: PAS domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 transmembrane" amino acids 38 to 61 (24 residues), see Phobius details amino acids 67 to 87 (21 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 104 to 232 (129 residues), 72.3 bits, see alignment E=2e-24 PF13188: PAS_8" amino acids 108 to 160 (53 residues), 24.7 bits, see alignment 6.7e-09 PF00989: PAS" amino acids 109 to 221 (113 residues), 40.3 bits, see alignment E=1.2e-13 PF08448: PAS_4" amino acids 116 to 227 (112 residues), 39.5 bits, see alignment E=2.3e-13 PF13426: PAS_9" amino acids 120 to 224 (105 residues), 41.6 bits, see alignment E=5.3e-14 PF07730: HisKA_3" amino acids 253 to 321 (69 residues), 55.4 bits, see alignment E=3e-18 PF02518: HATPase_c" amino acids 362 to 452 (91 residues), 37.6 bits, see alignment E=1.1e-12

Best Hits

KEGG orthology group: None (inferred from 91% identity to rpi:Rpic_4427)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (462 amino acids)

>ABZR87_RS20030 PAS domain-containing sensor histidine kinase (Ralstonia sp. UNC404CL21Col)
MGYVGCIPAHFWCSVAEQDTQSSKAAHRRLPQLQSTSAELVVGVLAIVLLAATVARLAVV
LPAGDGAFVLLAAASVAAVVALMFYGLRLRKLRAAVARDLTHLEKSEARLAGIIRSSMEA
IISVDDAQRIVLFNPMAETLFGCSARHAIGRPLSDFIPERFRGAHEAHVRRFGVTGVSER
QMGKQRPLFALHSDGREFPIEASISQIEVNGGKLFTVMLRDTTERVRAEAALRRSQEELQ
HLSDSVLATREEERHRIARELHDDLGQRLSALKMDISLLAADLQAARSDQTLIDQTQAMQ
RVIDETIAAVRQISADLRPPLLDELGLVPSIEWMAKNFRQRFGLVVNVHAQEVAMNERAA
ISVFRIVQEALNNVVRHADATRVEIEFSQQGDLLELSIQDNGHGWSGAPPAVGERKPLGL
LGIRERARLLGGQAMTSHAPGGGFRLSVRFPAVHKAPEEART