Protein Info for ABZR87_RS19540 in Ralstonia sp. UNC404CL21Col

Annotation: CpaE family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.

Best Hits

KEGG orthology group: K02282, pilus assembly protein CpaE (inferred from 97% identity to rpi:Rpic_4249)

Predicted SEED Role

"Type II/IV secretion system ATPase TadZ/CpaE, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (447 amino acids)

>ABZR87_RS19540 CpaE family protein (Ralstonia sp. UNC404CL21Col)
MDYFLLHGGARGGMQVDAQSAGVHRWLAAAIRELGVLVAETTGHDAFIEQIGAVNPEVVF
VRFASSPTLIDVPDQDQKLGEGTDAINEATQLVAQLTRLFPGLPLVAVGSAADGRAMLAA
LRAGVKDFVDVDGAPAEAVRVVRRLLAERASAEPTRRGRVLAVLGARPGVGATTLATNLA
TVVRRTSASDVMLLDLGQPLRDGALYLNVQANFHFVEAVRNLRRFDQVFVQTALSRHPNG
LAVLPLPISLAEMRDISFSEALGLLNRLRTFFDLQVVDLGGFGNIDFIAQIIKAADDVML
VTEQSVGAIVSAAELMQELKKREIDRDHLHLTISKFDTRLSLDAAQIAERLEIPSVLTVP
NRREALVIASNQGAMLAETHPTDAYVRALAQIAQTLGYAQQSERASGVSSWVSGVGARLG
GRFGGRSKRKSADATELDIGTTERNAT