Protein Info for ABZR87_RS19335 in Ralstonia sp. UNC404CL21Col

Annotation: glutamate cyclase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 200 400 600 800 1000 1200 1400 1600 1800 2000 2200 2400 2576 transmembrane" amino acids 2415 to 2432 (18 residues), see Phobius details PF16013: DUF4781" amino acids 683 to 866 (184 residues), 53.5 bits, see alignment 2.7e-18 PF14336: GLUCM-like_C" amino acids 1170 to 1446 (277 residues), 187.5 bits, see alignment E=5.6e-59 amino acids 1781 to 2045 (265 residues), 146.8 bits, see alignment E=1.4e-46 PF01177: Asp_Glu_race" amino acids 1477 to 1690 (214 residues), 72.8 bits, see alignment E=5.6e-24

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (2576 amino acids)

>ABZR87_RS19335 glutamate cyclase domain-containing protein (Ralstonia sp. UNC404CL21Col)
MPAIDEINGRIVYYRPPPPPPPPPTPEQKQTAADAKTRTDAAIQTANTAVNNYINNGDDS
KAAQATLDKPLSDVINSVQNELRRQADEAPAGSEKKAIEDAAAAIKKRDPDAKWLDKIVD
DAKDAVEKQDPSQRTASEARDGVLDAQDKLQDAQSIKVTNRTIAEDKQDSINTAQANLNK
AIQDFKTALGNELSTYENFGSGDNLKAANDAADALAKAHPDWDDGSLAFARNIATADAIQ
YQINHINPNDPTLSAQDKALATNDPVQFACVQLARPHANDKNAEQIYEQIGAASYDVRVN
YTKDQVAAKMKAGDAEGALKILSTNMNDVSVTSADPEARAHLYEVAGAPFFNAHSDYFNK
QISDLTQVYKYDPKDADSGKKMADGTVKYDAVGKWMKDLAKVAPPEVAGNLLTTVEDRFN
DNGHWFQSNSGDTSGLIPHGSDFYGGLSLTAAVADSPRFASDQPSTDHAQQVANWLTTNS
NAKSFLYSMQTSGSGGSMPSWVPVQNAVGDGNGATVTNALIQQHGKDLPNADMLQRAFDR
GNEKVQQKQAEADYKTFQADQNGGLKNIFGQMSKATFGKDNPLYNDKTQAFTGPDADTQR
KNYIGAALMIQADNAGAQASGDTNAAWYTSANGTKIINEVNKAIHDAGGDNPSVKAIPIA
YVDKSAGVMPTALFEVAGKDGKTHYIDDRGWDYSSLDDYRHNNALSDGGTIYLPKNLAGK
VGLDSNGVPDVDHFSAHITTTGQKIRHVVDIVAGVATAVGGVILSVGTFGGASIVGGAMV
AVGTGWIVGESVDHLHTLADHGRSWSPLNPEATNDWLAIVTSAAGEYSLAGKGLVAVSDV
ANASRLFKITRSASDLVAGGGGMIMTGAQVKDLLMYGDRMSGEQKAESIMFLGLGLGQVG
ATRMLERVGLSQGTERVGLLNALKNNADRYKPTEMAPEPTTVAANDPASAGRPTTDPTTE
RVITQAGGKTNEPTGSAPGSEGKDGSTGKPGTDPVDPATSKPKTAGEPTTEPGKTSPPGD
EGSPTNTTPARPSRPLPRALDDLANPEVTLTSFTDTQKALDAGTQNALSQHADLLLDAEN
YRTSGTTTGRHPRGIGVRRLAAALREMSDDQRKLILSKAEFAHDTANIKDPVRMSWRQRM
QLYRGKSSVFGRTADRIMSPVDRIQAMFIDRGIRNFFVKGGTEDAAAALMGKRILMVTGF
TVGRDPATGRLLPETDGPVGTGEKAATLAQAGYDITVATDSANMPVLKSVLDTYPGGHLV
KLELFDAKRGQPARDAANELLDRVQPEAVVAIELPARNADGDYLNMRGISVADVNAPKDQ
IILEANKRKGMITVGVGDGGNEAGMGGLRSKIPPVTLADGSTVDFASTVPVDFPVTAWNS
NFGAQAILANMLRNMGRLDLMPKPEQLHAAIKASVEAGAVDGVSRKGEASVDGFASQVHQ
GMLVLLRNAMNHMPDGKTFDEATPNEPFTVAAFDSSNGGLIAAKNMLAIIKAETGEDLQM
VPVVDHANAPYGPKSPDTLIRLVGNGLQTAQRLKAAMVAMACNTACTAFPKALDNVDVPV
INLIDVTSRAMVEHGGDRPAVIATAGTVKSGAYQNKVAELTHGEITPQAVAAHKFADFVN
DLKHKSDDPAVKAELQAASDKYVEELDPNTTSLWLCCTHYPAMKDFLVTSLQKRGMDIPV
IDPMEYQAKALLNEIGKSEWHTPSAAYSTDPYVVTSGKTGPVSESAHNLMERPDVPVQRV
RRFGPGKTLDGTIPPNPRMEPTPISNAVMAMFNPDMARIENPKGVDNAAAALQGSNRILV
LAGSRNAHGAVDTDGIAGAAVFGHDMQAAGKQVVYVVPHEAVPVLDAALQARGAAVNDYS
IVPFDAAPGEQARTTAQDLIHQESPDTIVSINVHGRNADGRYIDQDGNDVTDQTVPLDEV
VATGWKTNGVTTIGVGSRGHEAGMGNTRRTAPQVTLPDGTVVDPRSVVPADHYVSASNSN
WGAHGLAASALKAAGRTDLLSTHQQHMDALEASANAGAVDGVTGRADPTVGGHDTNTYQT
VVQMINLAAGKKPDVPPPTAANAAGPKGPEGPQPKDPASTTEPTGSKTTEPITAKTSEAG
NDGNGTPPTEPDSAANAGEPKRKPWIRWIFAGSLTGAFSTAASSATLTGSAATHAVFDPS
LTSPLSFMYRGSIAALRANKTRAINEQIGKLGTEDSAPALAWLKANVRDRAGRWGLSKTD
RAAIGEALDHFQANPDALTDALSKKDNPDAQTDRNVQRLQALTSAPAKLLSPKSPMGRAN
DTLQLLTLALNNGNTAYWFATHGAHLNTPAFWSNALFLSANLALSSRNFAGRLGATFNDK
ATNTSPWLNRAQAFTMSLYTVGSVPLAMNDALMHTNSPAIGATKAALDLAFGAGALRIAG
DLMPKIGQRLPSNAMLPGGVILGVAAVTRFGIELFVPNQAAKPAVAQVQANGNSNGQDQN
GQPISAFPLPDMQGVSGDVLRANAPHALPSVGTASSPQYAIVGPGDTLWQLSAADAAKLL
GTTAPASDARTAAALNKLPPMNSQFDWAALDGNPYTQGATGLDPDVVVPGDIVRIG