Protein Info for ABZR87_RS19225 in Ralstonia sp. UNC404CL21Col

Annotation: TOBE domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 TIGR00637: ModE molybdate transport repressor domain" amino acids 19 to 109 (91 residues), 100.7 bits, see alignment E=3.9e-33 PF00126: HTH_1" amino acids 23 to 84 (62 residues), 37 bits, see alignment E=2.7e-13 TIGR00638: molybdenum-pterin binding domain" amino acids 123 to 190 (68 residues), 73.3 bits, see alignment E=1.2e-24 PF03459: TOBE" amino acids 125 to 188 (64 residues), 61.7 bits, see alignment E=6.3e-21 amino acids 198 to 267 (70 residues), 39.6 bits, see alignment E=5e-14

Best Hits

KEGG orthology group: K02019, molybdate transport system regulatory protein (inferred from 96% identity to rpf:Rpic12D_4329)

Predicted SEED Role

"DNA-binding domain of ModE / Molybdate-binding domain of ModE" in subsystem Molybdenum cofactor biosynthesis or Transport of Molybdenum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (270 amino acids)

>ABZR87_RS19225 TOBE domain-containing protein (Ralstonia sp. UNC404CL21Col)
MLELDGTIWLRAGEDNWGGRGRIELLAAIGQTGSITAGAKAVGLSYKAAWDAIDTMNNLA
GEPLVVRTTGGKGGGGSVLTPRAQRLIESFRALEAEHRRFVERLDAAAQAASEDVNLLRR
LMLRTSARNTLFGTVESVAPGAVNDVVTLRLPGGQPVAATITQESTRVLGLAPGVQAVAL
VKAPAVMLMHGAGEWRVSAENQLPCVVTEIRDGAVQAEVRLRLLDATAASAGETVLVAML
SRTAVETLALAEGVEAVAVFEASSVILGLA