Protein Info for ABZR87_RS19180 in Ralstonia sp. UNC404CL21Col

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 204 to 224 (21 residues), see Phobius details PF00672: HAMP" amino acids 221 to 273 (53 residues), 64.3 bits, see alignment 1.5e-21 PF00512: HisKA" amino acids 277 to 338 (62 residues), 54.9 bits, see alignment E=1.1e-18 PF02518: HATPase_c" amino acids 390 to 500 (111 residues), 94.5 bits, see alignment E=8.7e-31

Best Hits

KEGG orthology group: K07642, two-component system, OmpR family, sensor histidine kinase BaeS [EC: 2.7.13.3] (inferred from 93% identity to rpf:Rpic12D_4320)

Predicted SEED Role

"Sensory histidine kinase BaeS"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (514 amino acids)

>ABZR87_RS19180 ATP-binding protein (Ralstonia sp. UNC404CL21Col)
MRPSFGITSKLFVALFMLSIVVALAMGAAVRWRFDANFLDYVNAREAERMASLAQGVEAA
YAQHGSWDFLRDDRMAWFRLLRREGARARANGMGGDRFDLPPGHRFDPLPPGMDKDAPPP
PGPPTAGRMPPHPPGEPPTPHSPIWLLDAQRNVIIGDGPPLGPNARWQELHHNGQTVGWL
AMPPRVRVPEGADQAFQAQQLRATWIIAGLSVLLAALVAVLLARGLLAPMRRLTDAARRM
ADGDYATRVDVHSRDELGELAADFNHLAASLEANQKMRRQLTADISHELRTPLAVLRGEL
EALEDGVRPLTATSLASLQAEVSTLSKLIDDLYELSLADVGALAFHMEPLDLADTVCSAV
QGFTPRLMEKCIALQLDVPAAPSHATMVNGDPQRLRQVMQNLLENTLRYTDAGGTLRVHV
HQEGGWQQIDVQDSAPGVPDAMLPRIFDRLFRVDASRSRAQGGAGLGLSLCQTIVAAHGG
TIEARHSPLGGLWIAIRLPVLDVLDPLADHDSDH