Protein Info for ABZR87_RS18660 in Ralstonia sp. UNC404CL21Col

Annotation: xylulokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 PF00370: FGGY_N" amino acids 1 to 243 (243 residues), 228.6 bits, see alignment E=9.4e-72 TIGR01312: xylulokinase" amino acids 3 to 481 (479 residues), 563.5 bits, see alignment E=1.6e-173 PF02782: FGGY_C" amino acids 253 to 442 (190 residues), 112.5 bits, see alignment E=2.4e-36

Best Hits

Swiss-Prot: 55% identical to XYLB_KLEPN: Xylulose kinase (xylB) from Klebsiella pneumoniae

KEGG orthology group: K00854, xylulokinase [EC: 2.7.1.17] (inferred from 70% identity to hse:Hsero_0446)

Predicted SEED Role

"Xylulose kinase (EC 2.7.1.17)" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Xylose utilization (EC 2.7.1.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (502 amino acids)

>ABZR87_RS18660 xylulokinase (Ralstonia sp. UNC404CL21Col)
MYLGIDLGTSEVKVLLLDATGTIVGTAGEPLTVSRPHPGWAEQTPENWWQATSAAIGKLR
DAAPEAFAATRAIGLSGQMHGAVLLDARNRVLRPAMLWNDTRSTAECLELTRRVPDLHAV
AGNLAMPGFTAPKLLWSARHEPDVFSAIDCVLLPKDYLRLRLTGERASDPSDAGGTLWLD
VARRTWSDELLAATGLSPSQMPRLVEGSAPSGALLPEVADAWGMARGVVVAGGGGDGAAS
AVGIGATQPGDGFLSLGTSGVIFVVNDRFRPNPAQAVHAFCHALPGRWHQMSVMLSAASC
LRWFCRLTSVPEATLLPEIAALAATEQTERQSAPFFLPYLSGERTPHNDAFAQGHFHNLT
HASDRAALGYAVLEGVAFGMADGLDALRAAGTQVASLSFVGGGSRSPFWAQLLADTLNTE
LTTHVGSEAGGALGAARLGWMADGGIEAAVCAKPPVQATYRPDAARHARLAERLSTFRAL
YRRASPLPVTPSAQTTDLPLPA