Protein Info for ABZR87_RS18545 in Ralstonia sp. UNC404CL21Col

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 PF00561: Abhydrolase_1" amino acids 39 to 154 (116 residues), 64.9 bits, see alignment E=1.4e-21 PF12697: Abhydrolase_6" amino acids 41 to 260 (220 residues), 53.5 bits, see alignment E=8.4e-18 PF12146: Hydrolase_4" amino acids 57 to 159 (103 residues), 39.5 bits, see alignment E=6.2e-14

Best Hits

KEGG orthology group: None (inferred from 98% identity to rpf:Rpic12D_4220)

Predicted SEED Role

"hydrolase-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (270 amino acids)

>ABZR87_RS18545 alpha/beta hydrolase (Ralstonia sp. UNC404CL21Col)
MAESLSAPSVDGTEAWITTPDGRLYARQWGGPVDDAAKPPIVLLHDSLGCVALWRDFPQR
LAQSTGHAVIAYDRLGFGQSDAYPGQLDPGFIQQEAYGGFAALTDQLGVDRFIVFGHSVG
GGMAVSIAAAYPGRCAGLITESAQAFVEEQTRQGIRIAQAQFAEPGQMGRLERYHGSKAQ
WVLDAWVNTWLSPAFAQWCLDDALLAVRSPVLALHGTEDEYGSTAQPERIVTLAGAPATL
KLVQRCGHVPHREQEAAVLAAVNAFLSASA