Protein Info for ABZR87_RS17775 in Ralstonia sp. UNC404CL21Col

Annotation: acyl-CoA dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02770: Acyl-CoA_dh_M
  • amino acids 127 to 213 (87 residues), 35.7 bits, E=8e-13
• PF08028: Acyl-CoA_dh_2
  • amino acids 241 to 377 (137 residues), 35 bits, E=1.6e-12

Best Hits

KEGG orthology group: K00249, acyl-CoA dehydrogenase [EC: 1.3.99.3] (inferred from 73% identity to reh:H16_B1481)

Predicted SEED Role

"Acyl-CoA dehydrogenase; probable dibenzothiophene desulfurization enzyme"

KEGG Metabolic Maps

• Fatty acid metabolism
• Propanoate metabolism
• Valine, leucine and isoleucine degradation
• beta-Alanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.3

Use Curated BLAST to search for 1.3.99.3

Protein Sequence (405 amino acids)

>ABZR87_RS17775 acyl-CoA dehydrogenase family protein (Ralstonia sp. UNC404CL21Col)
MNTPRDLHLPDRLQEALAELPALAQRIGTDAAAREVRRVLPYEAFAHFRASGLGLLRIPV
EWGGLGGSLVDLFETISTLAAHESNVAHALRIHYDLTEVIRLSPLDAFHRTQLDRLLEGA
LFGGGSTERGTSRPGEVTTTLQRDGADYRLSGRKYYTTGTAFADYGRFNVNDDAGGNVQI
IIPVTREGVKVIDDWDGMGQRMTASGSIVFEHVQVRADEVASRVSSSLVGRHTGALRQLH
LVAVAAGIVRNVAADARRYVVNHGRPVLHSPAPSAREDHFIQQVVGDIAAHSHAIDALVR
ENARVLDRSADAIRNEAENADALVLEGALATAQTQLVVGKLALHAAQQLFEAGGASMTAR
VHNFDRHWRNLRTIFSHNPLLHKARVVGDYHLNGQTQHLKEGRVF