Protein Info for ABZR87_RS17600 in Ralstonia sp. UNC404CL21Col

Annotation: bifunctional lysylphosphatidylglycerol flippase/synthetase MprF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 877 transmembrane" amino acids 37 to 60 (24 residues), see Phobius details amino acids 81 to 100 (20 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 159 to 181 (23 residues), see Phobius details amino acids 191 to 213 (23 residues), see Phobius details amino acids 234 to 256 (23 residues), see Phobius details amino acids 262 to 280 (19 residues), see Phobius details amino acids 287 to 304 (18 residues), see Phobius details amino acids 311 to 333 (23 residues), see Phobius details amino acids 353 to 373 (21 residues), see Phobius details amino acids 386 to 409 (24 residues), see Phobius details amino acids 417 to 434 (18 residues), see Phobius details amino acids 439 to 456 (18 residues), see Phobius details amino acids 476 to 496 (21 residues), see Phobius details amino acids 517 to 537 (21 residues), see Phobius details amino acids 854 to 869 (16 residues), see Phobius details PF03706: LPG_synthase_TM" amino acids 41 to 325 (285 residues), 48 bits, see alignment E=1.3e-16 PF09924: LPG_synthase_C" amino acids 564 to 849 (286 residues), 318 bits, see alignment E=5.4e-99

Best Hits

KEGG orthology group: K14205, phosphatidylglycerol lysyltransferase [EC: 2.3.2.3] (inferred from 97% identity to rpf:Rpic12D_4106)

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.2.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (877 amino acids)

>ABZR87_RS17600 bifunctional lysylphosphatidylglycerol flippase/synthetase MprF (Ralstonia sp. UNC404CL21Col)
MPDAASNDASPTPRRPSAHAAPAAPATPVRPDSGLGLAGWIVVGVVLVLGALVFDSLYAL
LDHVHYADMVAALQATPRSHLLLAVLATALSYVALTGYDASGLRYAGAHVAPATVATTSF
IAYALGNTVGLGSLTAGAVRSRLYTAAGVDAARVTEAVAFDAGALGVSTTAFGAVGLLWG
APHIAAIAHLPAALLEVVALLVLAGVVALLVLCMRQRHVTLFGRWEIRLPPPGLAARQFA
ISAADMIAAAAALWVLMPAGAVDLPTFVAFYALAVTLGVLSQSPGGLGVFEAVILLGCSG
QAPPAEVLAALLFYRVIYFLLPLVVAAAMLGAFELRAGAGAPFGRAAVKLSPGLLAALTM
VAGVMLLISGVTPASDEAEDLLRMHVPLFVVEASHMIGSVAGLIMLFVARGLLHRLDAAW
WAALVLSLLTGVLALPKGIAVSEMAVLVTLAVLLVISRRQFDRPSSLFSQRLEAGWLLAM
VCVFAACVWILFFAYREVAYANQLWWQFTFDGDAPRSIRALMAVAVTGLGFGMWQLFRKE
PGVTTFPSDEELARAAEIVRKQPAADATLALMGDKSLLFSPSGNAFIMYAKQGRSWVALS
DPVGAQQEWPELIWRFIEMADAHGGRAAFYKTRPQTLSLYLDAGLRAYKLGEEAYVSLPE
FSLKGSRRANLRHGVTRGEREGLSFEIIQTAEVPTVLDELRAISDEWLRNQNAREKGFSL
GAFEDRYICSQPVAVVRREGVILAFATLMCPDVLRIEASVDLMRYRSDVPPGTMDFLFGK
VILHFQAQGYQRFGLGMAPMSGMVEHQLAPRWHRFGRMMFRHGARFYNFRGLRNFKDKFE
PVWEARYLLARGGIAPLFTLTDVAALIGGGLKGVISK