Protein Info for ABZR87_RS17230 in Ralstonia sp. UNC404CL21Col

Annotation: glycogen synthase GlgA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details PF08323: Glyco_transf_5" amino acids 6 to 238 (233 residues), 235.6 bits, see alignment E=1.8e-73 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 6 to 480 (475 residues), 520.3 bits, see alignment E=2.3e-160 PF13579: Glyco_trans_4_4" amino acids 21 to 225 (205 residues), 30.8 bits, see alignment E=9.1e-11 PF13439: Glyco_transf_4" amino acids 21 to 226 (206 residues), 31.2 bits, see alignment E=5.5e-11 PF00534: Glycos_transf_1" amino acids 285 to 445 (161 residues), 61.3 bits, see alignment E=2.3e-20 PF13692: Glyco_trans_1_4" amino acids 302 to 444 (143 residues), 39.4 bits, see alignment E=1.8e-13

Best Hits

Swiss-Prot: 76% identical to GLGA_RALSO: Glycogen synthase (glgA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 97% identity to rpi:Rpic_3940)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (543 amino acids)

>ABZR87_RS17230 glycogen synthase GlgA (Ralstonia sp. UNC404CL21Col)
MTLSLNVLFVASEAVPLAKTGGLGDMVGACASALRRAGMKVTVMLPGYPDAITQLQHTRT
VCEWTDLPGGRARLLSGHMGAQGIPVLLFDAPALFARPGNPYLDAHGEPYEDNALRFAAF
SQAAARVAAGVPGVHRSDIVQAHDWHAGLVPLFVKRAQVPVKTVFTVHNLAFQGNFPMHV
VPDIGVPPDAAHEAEFWGQFSFLKAGLLWADRITTVSHAYAREILTDTAGCGMQDLLRAR
QQDLVAILNGIDNDVWNPSKDPLLPQPFVASNLSGKHTAKRVLQQRFGLPEDAKAPLLAL
GSRLTHQKMADVTLQALPQLLESNPQLQVAVLGCGEHAYETGMAELAARYPRQVAAKIGY
TEAYAHLLHAGADILLHGSRFEPCGLTPLYSMRYGTVPIASRVGGLMDTITDHGSPEAAM
HGATGFLFDGDTADAMVAAVERALHVFAQPQAWRILQYNGMTTDFGWSQPAREYIALYRT
LVPAATPMPAVALVQAPVAPDVVHTPRPDQPVRTPARRRSTALSDEIRAHAVARAASAEK
IRA