Protein Info for ABZR87_RS17135 in Ralstonia sp. UNC404CL21Col

Annotation: M20/M25/M40 family metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF01546: Peptidase_M20" amino acids 141 to 494 (354 residues), 56.7 bits, see alignment E=3.3e-19 PF07687: M20_dimer" amino acids 224 to 377 (154 residues), 46.5 bits, see alignment E=3.3e-16

Best Hits

KEGG orthology group: None (inferred from 97% identity to rpi:Rpic_3920)

Predicted SEED Role

"Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (497 amino acids)

>ABZR87_RS17135 M20/M25/M40 family metallo-hydrolase (Ralstonia sp. UNC404CL21Col)
MLGAAGLAGAAELSAADAERHAQATYREYFELLSLPNDAIVPEDVRKNADWLEQAFRRRG
FTTQQLANNGKPMLYAELPNPDAARKTVLFYMHLDGQPVIPAQWAQKSPWTPVLKHKTAQ
GNWEEIDSAQLFSGPLDPEWRVFGRSSADDKGPIMMMLAAIDALKASGGQPAVNVKIILD
SEEEKGSPSISKVMQANRELLRCDAIVIHDGPMHASNLPTLVFGNRGAAEARLTVYGAKV
PLHSGHYGNYARNPAQQLANLLASMKNDAGRVTVPGYYDHVKISAADRKIMAAVPDDQAA
LNKRLGIAHADKVGANYQEAMQYPSLNVRGMASAAVGDKVANIVPDKAVAELDLRTTPDS
TAGYLGKLIEQHIERQGYHLVKNAPTDEERSRYDKLATFTYQSEGADAAGSPIDSAVGTW
AYKSLTDTFGANPAPVRIRMMGGTVPTAEIVGVLQVPFAIIPLVNADNNQHAANENLRMG
NYVSGVRTLYGLLTHPL