Protein Info for ABZR87_RS17030 in Ralstonia sp. UNC404CL21Col

Annotation: ionic transporter y4hA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details amino acids 34 to 54 (21 residues), see Phobius details amino acids 65 to 88 (24 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 212 to 233 (22 residues), see Phobius details amino acids 249 to 269 (21 residues), see Phobius details amino acids 282 to 306 (25 residues), see Phobius details amino acids 317 to 333 (17 residues), see Phobius details amino acids 340 to 359 (20 residues), see Phobius details PF01699: Na_Ca_ex" amino acids 34 to 187 (154 residues), 70.8 bits, see alignment E=6.7e-24 amino acids 216 to 358 (143 residues), 48.8 bits, see alignment E=4e-17

Best Hits

Swiss-Prot: 52% identical to Y4HA_SINFN: Putative ionic transporter y4hA (NGR_a03490) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K07300, Ca2+:H+ antiporter (inferred from 99% identity to rpf:Rpic12D_4012)

Predicted SEED Role

"Calcium/proton antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>ABZR87_RS17030 ionic transporter y4hA (Ralstonia sp. UNC404CL21Col)
MALSSNKLPPWTVAAPLLAWVVLVGGSFMTPPGWLIALMALALAGAVFAAVHHAEVVAHK
VGEPFGTLVLAIAVTVIEVALIVSVMLSSGPEKAGLARDTVFAAVMLICNGIVGVCLFVG
GLRHREQAFQAPGATAALAVLAALVTLTMVLPNYTSSTPGPVMTSSQLAFAGVTSLVLYG
CFVIVQTIRHRDYFLVDSANEDVHAPPPPARVAALSAVLLMASLVAVVGLAKVLSPSVEA
AILNAGAPPATVGIVIAALVLLPECLAALRAANADRIQTSLNLALGSALASIGLTIPTVA
AVFIWIGRPLELGLGPKEMVLLFLTLIVSSLTLGKGRTTILQGVVHLAIFAAYLFLSIVP