Protein Info for ABZR87_RS15750 in Ralstonia sp. UNC404CL21Col

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 26 to 368 (343 residues), 234.6 bits, see alignment E=4.1e-73 PF13433: Peripla_BP_5" amino acids 27 to 371 (345 residues), 98.7 bits, see alignment E=5.7e-32 PF01094: ANF_receptor" amino acids 63 to 352 (290 residues), 50 bits, see alignment E=3.7e-17

Best Hits

Swiss-Prot: 48% identical to LIVB6_BRUME: Leu/Ile/Val-binding protein homolog 6 (BMEII0633) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 97% identity to rpi:Rpic_2449)

Predicted SEED Role

"ABC transporter substrate-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (389 amino acids)

>ABZR87_RS15750 ABC transporter substrate-binding protein (Ralstonia sp. UNC404CL21Col)
MKRRVLLLTAVAGALMIGLPAFADEPIKIGLIAPFSGPFADYGKQMEDGIKAYQKLHGTT
AGGRQVQIIVKDTTGPVPDVAKRLAQELVVRDKVDFLAGFGLTPEALAVAPIAQQAKKPM
VIFNAASSSITTKSDYVTRVSMTLPQISTPIASWALKNGIKQVATVVADYAPGIDAENAF
KQTFTAGGGQVVEAVRAPLRNPEFAPFIQRVKDTKPQAVFVFLPAGEQGVAFMKGFRERG
LAQAGIKVIATGDLTDDHVLPAMGDSTLGVITSFHYSAAHDSAQNKTFLKAFADANPGAG
RPNFMAVAAYDGIGAIYNVINKLGGKIDGEKAMAAFKGMKIDSPRGPITIDPATRDVVQT
VYIRKVEKVGNELYNVEFDKFADVKDPGK