Protein Info for ABZR87_RS15400 in Ralstonia sp. UNC404CL21Col

Annotation: helicase HerA-like C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 PF05872: HerA_C" amino acids 5 to 520 (516 residues), 815.2 bits, see alignment E=2.2e-249 PF01935: DUF87" amino acids 19 to 223 (205 residues), 36.3 bits, see alignment E=6.8e-13

Best Hits

Swiss-Prot: 67% identical to YJGR_ECOLI: Uncharacterized protein YjgR (yjgR) from Escherichia coli (strain K12)

KEGG orthology group: K06915, (no description) (inferred from 98% identity to rpf:Rpic12D_1987)

Predicted SEED Role

"ATPase component BioM of energizing module of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>ABZR87_RS15400 helicase HerA-like C-terminal domain-containing protein (Ralstonia sp. UNC404CL21Col)
MTDPILIAKNAKAELVLLPQLANRHGLITGATGTGKTVTLQTIAQGLSKIGVPVFLADVK
GDLTGISQPGQSNDKLKARLRERGLEEPQWAGCPVTLWDVYGERGHPVRATVSDMGPLML
SRMLELNDIQTGVLNLVFKIADDSGLALLDMKDLRAMLQHVGEHASDYTNKYGNISSASI
GAIQRNLIALEEQGADQFFGEPMLDINDLMQTVRGQGVINILAADKLLNAPKLYATFLLW
MLSELFEHLPEVGDVDKPKLAFFFDEAHLLFNDAPPSLLQKVEQVVRLIRSKGVGVYFVT
QNPADVPDTVLGQLGNRVQHALRAFTPRDQKAVKAAATTMRANPEFSIEEAIGELAVGEA
LISMLDEGGRPEITQRAFVVPPASRIGPISDDERRALMTNSLVAGRYDTAIDRESAYEIL
SGRVAKGGAASAPAPGSIGTDFGASTGSAPAPAPAPAQQESGGGWLGDVGSILTKGTGRS
GRGDSIVETLAKSTMRTIGSTVGREIVRGVLGSILGGSKKR