Protein Info for ABZR87_RS15070 in Ralstonia sp. UNC404CL21Col

Annotation: urate hydroxylase PuuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 85 to 109 (25 residues), see Phobius details amino acids 116 to 138 (23 residues), see Phobius details amino acids 150 to 171 (22 residues), see Phobius details amino acids 177 to 197 (21 residues), see Phobius details amino acids 229 to 246 (18 residues), see Phobius details amino acids 252 to 271 (20 residues), see Phobius details amino acids 279 to 299 (21 residues), see Phobius details PF06181: Urate_ox_N" amino acids 4 to 299 (296 residues), 469.8 bits, see alignment E=1.9e-145

Best Hits

KEGG orthology group: None (inferred from 99% identity to rpf:Rpic12D_1932)

Predicted SEED Role

"conserved hypothetical membrane protein, paralogue of Y20848"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>ABZR87_RS15070 urate hydroxylase PuuD (Ralstonia sp. UNC404CL21Col)
MEGYILDWANLLLRWLHVIVAIAWIGSSFYFVWLDNSLTKPTAPDLKDKGVDGELWAVHG
GGFYNPQKYLLAPKQLPDHLHWFYWESYSTWMSGFALLTVVYLFNANVYMIDRSVFDMTA
TTAVLLALGFLVVGWLVYDTICRVFGKNDRVVGILVAIYVVIAAFAACHLFSGRAAFLLI
GAMIATIMSANVFFWIIPGQRKVVASLKAGEKPDPIHGKRGKQRSVHNTYFTLPVLFAML
SNHYSMTYAAKYNWVVLVLIMLAGVLIRQFFILKHKGVVNWGYPAAGVAVLLGVAVWLAP
VSRPAAPVAEAPAATAPVAAAEGSASAPAAAGLATAAAAGGSDFAKVQAVVTARCYQCHS
AHPTLMPSPAKGVLLDTPEELGKHAQLVYQQVVQQKLMPLGNVTQITDDERTIIAKWFEG
GAKTN