Protein Info for ABZR87_RS15030 in Ralstonia sp. UNC404CL21Col

Annotation: substrate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF12849: PBP_like_2" amino acids 31 to 253 (223 residues), 145.8 bits, see alignment E=2.2e-46 PF13531: SBP_bac_11" amino acids 38 to 261 (224 residues), 44.8 bits, see alignment E=1.4e-15

Best Hits

Swiss-Prot: 41% identical to TUPA_CAMJE: Tungstate-binding protein TupA (tupA) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

KEGG orthology group: K05772, putative tungstate transport system substrate-binding protein (inferred from 95% identity to rpf:Rpic12D_1920)

Predicted SEED Role

"ABC-type tungstate transport system, periplasmic binding protein" in subsystem ABC transporter tungstate (TC 3.A.1.6.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (282 amino acids)

>ABZR87_RS15030 substrate-binding domain-containing protein (Ralstonia sp. UNC404CL21Col)
MPGLSKALRLPALICLTLAVASAAYAGDLRMATTTSTENSGLLKVLLPKFEAATGVHVQV
IAVGTGKAVKLGESGDVDVVLVHARQLEDAFVASGGGIDRRDVMYNDFILVGPDTDPAHV
RGQKNVIQGMETIAVAGEKAGAKFISRGDNSGTDVMEKAYWKTANIDPKGKPWYVSAGLG
MGEVLNMAAQMNAYTLSDRATYGAYRAKTGLDIVLAGDPRMFNPYGIIAVNPKKHPGINY
ADATKLIEWITSPAGQQVIADFKVNGEQVFFPNYGKAVASGK