Protein Info for ABZR87_RS14900 in Ralstonia sp. UNC404CL21Col

Annotation: NAD(P)H-quinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 TIGR02824: putative NAD(P)H quinone oxidoreductase, PIG3 family" amino acids 1 to 332 (332 residues), 479.8 bits, see alignment E=1.8e-148 PF08240: ADH_N" amino acids 28 to 103 (76 residues), 30.8 bits, see alignment E=3.4e-11 PF00107: ADH_zinc_N" amino acids 160 to 281 (122 residues), 102.2 bits, see alignment E=3.2e-33 PF13602: ADH_zinc_N_2" amino acids 192 to 331 (140 residues), 82.5 bits, see alignment E=8.4e-27

Best Hits

KEGG orthology group: K00344, NADPH2:quinone reductase [EC: 1.6.5.5] (inferred from 98% identity to rpi:Rpic_2217)

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (334 amino acids)

>ABZR87_RS14900 NAD(P)H-quinone oxidoreductase (Ralstonia sp. UNC404CL21Col)
MKAIEITQYGGPEVLQLGERPMPEAKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDI
PGLEVAGEIVSGDLTHADNRYGLKAGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDVE
AAALPENYFTVWSNVFDRGLLGRGAHGAEETLLVQGGSSGIGTTAIQIASALGHRVFATA
GSADKCAACVELGATRAINYKTEDFVEIVKAETGRGADVVLDMVGGSYVAREIACTADDG
RIVLIALLGGAKAEVPLGDILRRRITLTGSTLRPRPVAFKAAIAANLYETVWPLLSSGRI
KPVVHEVMPAAQAAQAHALMESSAHIGKIMLVWD