Protein Info for ABZR87_RS14830 in Ralstonia sp. UNC404CL21Col

Annotation: NADH-quinone oxidoreductase subunit NuoK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00420: Oxidored_q2
  • amino acids 8 to 103 (96 residues), 102 bits, E=6.3e-34

Best Hits

Swiss-Prot: 100% identical to NUOK_RALPJ: NADH-quinone oxidoreductase subunit K (nuoK) from Ralstonia pickettii (strain 12J)

KEGG orthology group: K00340, NADH dehydrogenase I subunit K [EC: 1.6.5.3] (inferred from 100% identity to rpi:Rpic_2204)

MetaCyc: 49% identical to ferredoxin-plastoquinone oxidoreductase subunit E (Synechococcus elongatus PCC 7942 = FACHB-805)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• aerobic respiration III (alternative oxidase pathway) (2/3 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• NAD(P)/NADPH interconversion (3/6 steps found)
• Fe(II) oxidation (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Protein Sequence (103 amino acids)

>ABZR87_RS14830 NADH-quinone oxidoreductase subunit NuoK (Ralstonia sp. UNC404CL21Col)
MSSLSLAHYLVLGAVLFAISIVGIFLNRKNVIVLLMAIELMLLAVNLNFVAFSHYLGDLA
GQVFVFFILTVAAAESAIGLAILVVLFRNLDTINVDDLDSLKG