Protein Info for ABZR87_RS14405 in Ralstonia sp. UNC404CL21Col

Annotation: MotA/TolQ/ExbB proton channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 128 to 153 (26 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details PF01618: MotA_ExbB" amino acids 101 to 206 (106 residues), 106.5 bits, see alignment E=4.2e-35

Best Hits

Swiss-Prot: 42% identical to EXBB_XANCB: Biopolymer transport protein ExbB (exbB) from Xanthomonas campestris pv. campestris (strain B100)

KEGG orthology group: K03561, biopolymer transport protein ExbB (inferred from 97% identity to rpi:Rpic_2117)

Predicted SEED Role

"MotA/TolQ/ExbB proton channel family protein" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (242 amino acids)

>ABZR87_RS14405 MotA/TolQ/ExbB proton channel family protein (Ralstonia sp. UNC404CL21Col)
MQELGLSHLWTQGDIVTRATAILLLIMSLASWIVILTKAWDIVRLKSMAQGAEKRFWHSD
DFDHAMQTLGSPKDNPFHTLAQTGREAAQHHRASQPQLHDVMDISDWITRSLKSAIDESV
GQMQSGLAVLASVGSTAPFVGLFGTVWGIYHALLGIGAVGVPTIDKVAGPVGESLIMTAF
GLAVAIPAVLGYNALTRGNKAIIAKLNRFAHDLHAYFVTGARLRPGAPRDEAGVRLAAVK
QQ