Protein Info for ABZR87_RS14315 in Ralstonia sp. UNC404CL21Col

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 765 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF20256: MoCoBD_2" amino acids 48 to 106 (59 residues), 35 bits, see alignment 1.2e-12 amino acids 637 to 719 (83 residues), 56.1 bits, see alignment E=4.4e-19 PF02738: MoCoBD_1" amino acids 360 to 594 (235 residues), 98.2 bits, see alignment E=4.3e-32

Best Hits

KEGG orthology group: K07303, isoquinoline 1-oxidoreductase, beta subunit [EC: 1.3.99.16] (inferred from 97% identity to rpi:Rpic_2090)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (765 amino acids)

>ABZR87_RS14315 xanthine dehydrogenase family protein molybdopterin-binding subunit (Ralstonia sp. UNC404CL21Col)
MNAKATKPRSGRRRFLLGALGIGGALVVGWGVMPPRSRVGDPGIFPEHNGEIALNGWIKI
TPEGNVVLAMPRVEMGQGIHTALSMLAAEELDIPLSRVGIESAPVERIYGNVVAMGDSSL
PLHPDSADKTWARALHWIMAKSAREIGLIITGGSSSTADGWQPVREAAATARAALVEAAA
RAWNVPAADVSIREGLLIGPGGKQSTFGEMAKSARGISAPSSVTLKPASQFQLIGKPAPR
NDLAAKTDGSARFSIDTRLPGMLYAAVVMCPVFGGKLKTFQSKAALGMPGVRYVVPFEGT
GGGAPGVAVVADHYWQARQALATLEPVWDNGPHAKLDSAGIRQQLVSALDSDKGGFTYRS
MGDGLKAFDKADGATLVEAEYSAPYLAHATMEPINCTAQVTADGVHLWAPTQVATLAQLV
AARAAGVSGDKVHIDIPLIGGGFGRRLESDFIGQAVTIATKTEGKPVQVIWSREEDVRHD
FYRPHAIARLKARVENGKVTAIASRSAGQSILAGELDRLFGAPSAGIDRYTAEGLFDLPY
EIEHEHIAHLAVDLPVPVGFWRSVGHSYNGFFMEGFLNEVATQAKLDPLAMRRELLKDHP
RELKVLDTAAQAAGWGQPLAPAADGAPRARGIALHPSFGSVVAQVVEVSMKDGKPRVHRV
VCAVDCGTVVNPGIVAQQMESAVIFGLTAALYGRIDIKDGQVVQSNFPDYPALKMAETPV
IETHFVPSTAEPSGMGEVGVPPIAPAVAHAVAQLTGKPVRQLPMV