Protein Info for ABZR87_RS14065 in Ralstonia sp. UNC404CL21Col

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 723 TIGR03705: polyphosphate kinase 1" amino acids 9 to 687 (679 residues), 974.3 bits, see alignment E=1.7e-297 PF13089: PP_kinase_N" amino acids 10 to 114 (105 residues), 118.3 bits, see alignment E=4.7e-38 PF02503: PP_kinase" amino acids 124 to 305 (182 residues), 193.7 bits, see alignment E=6.1e-61 PF17941: PP_kinase_C_1" amino acids 333 to 502 (170 residues), 245.1 bits, see alignment E=7.2e-77 PF13090: PP_kinase_C" amino acids 513 to 680 (168 residues), 216.7 bits, see alignment E=3.9e-68

Best Hits

Swiss-Prot: 71% identical to PPK1_BURVG: Polyphosphate kinase (ppk) from Burkholderia vietnamiensis (strain G4 / LMG 22486)

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 99% identity to rpf:Rpic12D_1711)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (723 amino acids)

>ABZR87_RS14065 polyphosphate kinase 1 (Ralstonia sp. UNC404CL21Col)
MSTLPAGDLLNRELGILEFNARVLAQAADPGVPLMERLKFICIVSSNLDEFFEIRIAGLK
EQMRDNPSSVTPDGLSVQQAFGVVSERVRQLVAQQYAMLQDEILPLLEKEGVFFHMTTNW
NEAQRAWCRSFFQRELVPILTPMALDPAHPFPRVLNKSLNFIIELSGKDAFGREAELAIV
QAPRALPRLVQMPPELSGYQYGFVLLSSFMQGFVHELFPQIDVHGCYQFRVTRNSDLFVS
EDEITDLREALQGELSTRHFGDAVRLEIAHDTSPALVVRLLQEFGLTEADCYRVKGPVNL
VRLLQVPDMVDKPVLKYPPHVPATVRQVANSSNVFDAIRQGDILLHHPYESFTPVLELLQ
QAARDPDVVAIKQTVYRTGNESTVMEALIKAARNGKEVTVVVELLARFDEETNINWADQL
ESAGAHVVYGVVGHKCHAKMLLVVRREVSGKGKTVKLRRYAHLGTGNYHPKTARLYTDFG
LMTANDQICEDVHHVFQLLTGTGAQVKLHHLWHSPFTMHDNLIEHIRAEARAARAGKRAR
IIGKMNALLEPTIIDELYKASRAGVKVDLIVRGVCALKPGVPGLSENITVRSIVGRFLEH
HRVYYFHAGGEEVVYLSSADWMDRNLFRRVEVAFPVLDRKLKARVIKESLQVHLRDNASA
WIMQQDGRYVQRQTRGKHVRVSQLELLNHFSPQAAAAAETAAAVAAATAAEPTVRAPVEI
SAG