Protein Info for ABZR87_RS14060 in Ralstonia sp. UNC404CL21Col

Annotation: exopolyphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 TIGR03706: exopolyphosphatase" amino acids 8 to 315 (308 residues), 317.1 bits, see alignment E=5.9e-99 PF02541: Ppx-GppA" amino acids 42 to 316 (275 residues), 235.3 bits, see alignment E=9.9e-74 PF21447: Ppx-GppA_III" amino acids 324 to 496 (173 residues), 135.7 bits, see alignment E=1.5e-43

Best Hits

KEGG orthology group: K01524, exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC: 3.6.1.11 3.6.1.40] (inferred from 98% identity to rpi:Rpic_2018)

Predicted SEED Role

"Exopolyphosphatase (EC 3.6.1.11)" in subsystem Phosphate metabolism (EC 3.6.1.11)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.11 or 3.6.1.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (512 amino acids)

>ABZR87_RS14060 exopolyphosphatase (Ralstonia sp. UNC404CL21Col)
MSPTPRLLAAVDMGSNSFRLMIGRVDETPGANGASSAQIFQVDALREPVRLAAGLTQDKY
LDQPARRRGVDALRRFGDRLRDFPPEHVRAVATNTLRVAKNAQEFLIEAEAALGFPIEVI
AGREEARLIYLGASHDAPACQGNRLVVDIGGGSTEFIIGNGYKPKLMESLYIGCVSHSRH
FFPNGNVDEYAMKQAELAARREIQVLVQQYRTAGWNQAVGSSGTARALAELIELNGFNDK
SNEHGITREGLERLKRALVKSENTNRLKLNGLKADRIPVLPGGLSIMLGVFAELDVDRMD
VTDGALRLGVLYDLLGRTHHEDMRTVTIEQFMRRYNVDRAQASRVRDAATALLSQFPDPP
DERREDNLALLGWAANLHEIGMSISHSGYHKHSAYIASHADMPGFSKTDQARLATLLLGH
AGKLGKLSGGGKFLDWRMLFSLRLAFVLCRRRGAIQLPGLRVRHSEGELNEGGFEVELPK
SWIEQNPLVEYSLMKEADEWQRIGRRYKVVYV