Protein Info for ABZR87_RS14050 in Ralstonia sp. UNC404CL21Col

Annotation: phosphohistidine phosphatase SixA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00249: phosphohistidine phosphatase SixA
  • amino acids 1 to 133 (133 residues), 79.7 bits, E=1e-26
• PF00300: His_Phos_1
  • amino acids 3 to 75 (73 residues), 42.8 bits, E=2.5e-15

Best Hits

KEGG orthology group: K08296, phosphohistidine phosphatase [EC: 3.1.3.-] (inferred from 97% identity to rpi:Rpic_2016)

Predicted SEED Role

"Phosphohistidine phosphatase SixA"

KEGG Metabolic Maps

• Aminosugars metabolism
• Ascorbate and aldarate metabolism
• Ether lipid metabolism
• Fructose and mannose metabolism
• Lipopolysaccharide biosynthesis
• Nicotinate and nicotinamide metabolism
• Riboflavin metabolism
• Sphingolipid metabolism
• Thiamine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.-

Use Curated BLAST to search for 3.1.3.-

Protein Sequence (157 amino acids)

>ABZR87_RS14050 phosphohistidine phosphatase SixA (Ralstonia sp. UNC404CL21Col)
MNLILWRHAEAEDVAASLRIQRNTDLQRELTKRGHKQAEKMADWLRPRLPDDTLVLASPA
VRTQQTARALTQHFQTLTALAPGADVSEILDALDWPSNTNLLLVGHQPWLGRLASLLIAG
TEMDWSVKKAGVWWLCRRMREDEAQTVLRAVVNPDLV