Protein Info for ABZR87_RS13480 in Ralstonia sp. UNC404CL21Col

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 211 PF00072: Response_reg" amino acids 15 to 125 (111 residues), 96.1 bits, see alignment E=1.5e-31 PF00196: GerE" amino acids 152 to 206 (55 residues), 69.5 bits, see alignment E=1.4e-23

Best Hits

Swiss-Prot: 45% identical to FIXJ_BRADU: Transcriptional regulatory protein FixJ (fixJ) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: None (inferred from 99% identity to rpf:Rpic12D_1621)

Predicted SEED Role

"Nitrogen regulation protein NR(I)" in subsystem Ammonia assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (211 amino acids)

>ABZR87_RS13480 response regulator transcription factor (Ralstonia sp. UNC404CL21Col)
MSTTPAAVAPRNETVFVVDDDEAMRDSLTWLLEGNGYTVRTYRSAEEFLVDDKRGEGVGC
LILDVRMQGMSGPELQDRLLAENSRMPIVFVTGHGDVPMAVSTMKKGAVDFIEKPFDESE
LRELVERMLSKARSEDSVAREQKAAKDLLGRLTTREQQVLERIVAGRLNKQIADDLGISI
KTVEAHRANIMEKLNVNTVADLLRLALSRNA